Analysis of Global Research Trends on Airborne Nanoparticles and Infertility in the Last Two Decades: A Scientometric and Topic Mapping Approach

Document Type : Review paper

Authors

1 PhD student , Population Health Department, Population Center, Imam Hossein University, Tehran, Iran

2 Assistant Professor, Faculty member, Department of Sociology, Faculty of Humanities, University of Arak, Arak, Iran.

3 PhD student in Nanobiotechnology, Imam Hossein University, Tehran, Iran

Abstract

In the present study, global research on the impact of airborne nanoparticles on infertility over the past two decades (2000–2024) was analyzed using a scientometric and thematic mapping approach. Findings indicate that since the early 2000s, initial research has primarily focused on the mechanisms of acute nanoparticle toxicity, such as oxidative stress and DNA damage. With the advancement of technology and growing environmental concerns, the second decade (2010–2020) witnessed a shift toward investigating chronic and transgenerational effects, particularly on sperm quality and fetal health. Thematic mapping identified three main clusters: the toxicological mechanisms cluster (oxidative stress and apoptosis), the animal studies cluster (effects on sperm and testicular function), and the human research cluster (hormonal disruptions and infertility). Scientometric analysis revealed a growth in publications, especially in Europe and Asia. However, noticeable gaps were observed regarding the effects on women, long-term consequences, and protective strategies (such as antioxidants). This analysis highlights the need to develop comprehensive theoretical frameworks, standardize toxicity assessment protocols, and implement policies aimed at reducing exposure to nanoparticles.

Keywords

References

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Governance of Population and Family
Volume 2, Issue 3 - Serial Number 5
September 2024
Pages 117-139

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History

  • Receive Date: 05 July 2025
  • Revise Date: 02 August 2025
  • Accept Date: 23 September 2025
  • Publish Date: 02 October 2025

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